| |
Treatment |
Adjusteda mean difference from placebo |
| Trial/treatment |
n |
Adjusted mean (SE) |
Mean (SE) |
P value |
95% CI |
| Study 1222.39 |
|
|
|
|
|
| Placebo |
99 |
-0.054 (0.020) |
|
|
|
| Olodaterol 5 µg |
100 |
0.131 (0.020) |
0.185 (0.020) |
<0.0001 |
0.145, 0.224 |
| Olodaterol 10 µg |
99 |
0.152 (0.020) |
0.207 (0.020) |
<0.0001 |
0.167, 0.246 |
| Tiotropium 18 µg |
99 |
0.119 (0.020) |
0.173 (0.020) |
<0.0001 |
0.133, 0.212 |
| Study 1222.40 |
|
|
|
|
|
| Placebo |
105 |
-0.008 (0.019) |
|
|
|
| Olodaterol 5 µg |
115 |
0.189 (0.019) |
0.197 (0.017) |
<0.0001 |
0.163, 0.231 |
| Olodaterol 10 µg |
106 |
0.213 (0.019) |
0.213 (0.019) |
<0.0001 |
0.186, 0.255 |
| Tiotropium 18 µg |
112 |
0.213 (0.019) |
0.221 (0.017) |
<0.0001 |
0.187, 0.255 |
|
