| |
Treatment |
Adjusteda mean difference from placebo |
| Trial/treatment |
n |
Adjusted mean (SE) |
Mean (SE) |
P value |
95% CI |
| Study 1222.39 |
|
|
|
|
|
| Placebo |
99 |
-0.095 (0.021) |
|
|
|
| Olodaterol 5 µg |
100 |
0.036 (0.021) |
0.131 (0.021) |
<0.0001 |
0.090, 0.173 |
| Olodaterol 10 µg |
99 |
0.082 (0.021) |
0.178 (0.021) |
<0.0001 |
0.136, 0.219 |
| Tiotropium 18 µg |
99 |
0.027 (0.021) |
0.123 (0.021) |
<0.0001 |
0.081, 0.164 |
| Study 1222.40 |
|
|
|
|
|
| Placebo |
105 |
-0.059 (0.018) |
|
|
|
| Olodaterol 5 µg |
115 |
0.094 (0.018) |
0.153 (0.018) |
<0.0001 |
0.117, 0.188 |
| Olodaterol 10 µg |
107 |
0.111 (0.018) |
0.170 (0.018) |
<0.0001 |
0.134, 0.205 |
| Tiotropium 18 µg |
112 |
0.105 (0.018) |
0.164 (0.018) |
<0.0001 |
0.128, 0.199 |
|
