Group Healthy n = 22 COB-1 n = 40 COB 2 n = 25 COB-3 n = 23 P2-1 P 3-1 P 3-2 IL-8 pg / ml 23,9 ± 3,31 40,6 ± 1,18 53,5 ± 2,14 76,2 ± 5,0 p <0,01 p <0,01 p <0,05

Table 2: Indicators of IL-8 in patients with COB in teenager’s severity of the disease