Tobramycin Colistin AZLI
Reason Yes No Yes No Yes No
Coexisting tendency for BHR 35,84 81,88 10,92 - - -
Tonicity of the solution 35,81,88 35,88 10,103 34 - -
Concentration/dose of the solution 88 35,84 - - 109,110 -
Active molecule itself - - 10 - - -
Presence of preservatives 35,77,82,84 - - - - -
Table 3: Possible reasons for BHR related to the inhalation of nebulized tobramycin and colistin (presented as citing reference)