

CMV: Conventional mechanical ventilation; HFNC: High flow nasal cannula; HFT: High flow therapy; LCL: Lower confidence limit; n: population; nCPAP: nasal continuous positive airway pressure; UCL: Upper confidence limit; VON: Vermont Oxford Network; x: number of patients. ^{a}Exact 95% binomial confidence limits. ^{b}Note that high flow nasal cannula therapy is the VON definition (cannula flow rate above 1 L/min), so much of the HFNC use in the VON group is not how we define HFT (flow rates between 3 L/min and 8 L/min, commonly in the 4 L/min to 6 L/min range). 

Table 3: Comparison of interventions in the 5 HFT study centers and the VON database from 20092011. 