Outcome 5 HFT Centers
x/n (%) (LCL, UCL)a
VON Database
(%)
Odds Ratio
Mortality 163/1363 (12.0) (10.3, 13.8) 13.6 0.88
Pneumothorax 66/1363 (4.8) (3.8, 6.1) 4.4 1.09
Nosocomial infection 202/1363 (14.8) (13.0, 16.8) 15.1 0.98
O2 at 28 days 693/1363 (50.8) (48.1, 53.5) 47.0 1.08
O2 at 36 weeks 331/1363 (24.3) (22.0, 26.7) 30.4 0.80
O2 at home 85/1363 (6.2) (5.0, 7.7) 12.5 0.50
ROP stage
0
1
2
3
4
5
  1113/1363 (81.7) (79.5, 83.7)
101/1363 (7.4) (6.1, 8.9)
115/1363 (8.4) (7.0, 10.0)
31/1363 (2.3) (1.6, 3.2)
3/1363 (0.2) (0.0, 0.6)
0/1363 (0.0) (0.0, 0.3)
  68.8
14.4
10.6
6.0
0.2
0.1
  1.19
0.51
0.79
.038
1.00
0.00
ROP surgery 30/1363 (2.2) (1.5, 3.1) 3.2 0.69
IVH grade
0
1
2
3
4
  1054/1363 (77.3) (75.0, 79.5)
136/1363 (10.0) (8.4, 11.7)
102/1363 (7.5) (6.1, 9.0)
24/1363 (1.8) (1.1, 2.6)
47/1363 (3.4) (2.5, 4.6)
  75.4
10.8
5.6
3.5
4.7
  1.03
0.93
1.34
0.51
0.72
Mean days in hospital 62.0 60.7  
HFT: High flow therapy; IVH: Intraventricular hemorrhage; LCL: Lower confidence
limit; n: population; ROP: Retinopathy of prematurity; UCL: Upper confidence limit;
VON: Vermont Oxford Network; x: number of patients.
aExact 95% binomial confidence limits.
Table 4: Respiratory related outcomes for the 5 HFT centers compared to the VON database for 2009-2011.