Atrial No atrial p value
Dilatation dilatation
Patients, N 2,268 5,409  
Clinical characteristics
Age (years) 68±16 65±17 <0.001
Gender (males) 1,012 (45%) 2,485 (46%) 0.289
Cancer 390 (17%) 940 (17%) 0.847
Chronic heart failure 368 (16%) 418 (7.7%) <0.001
Chronic lung disease 382 (17%) 684 (13%) <0.001
Physical examination
Heart rate (bpm) 97±21 92±20 <0.001
Systolic blood pressure levels (mm Hg) 127±23 131±23 <0.001
Electrocardiogram
Atrial fibrillation 305 (13%) 352 (6.5%) <0.001
Right bundle branch block 608 (29%) 749 (15%) <0.001
S1Q3T3pattern 624 (30%) 797 (16%) <0.001
Laboratory tests
Creatinine levels >1.2 mg/dL 507 (22%) 845 (16%) <0.001
PO2 levels (mm Hg) (N=5,215) 62±19 68±22 <0.001
Sat O2 levels (%) (N=5,438) 89±7 92±6 <0.001
Echocardiogram
RA diameter (cm) (N=207) 4.3±1.5 3.3±1.6 <0.001
Visualization of thrombus 105 (4.6%) 67 (1.2%) <0.001
RV hypokinesis 1,185 (52%) 562 (10%) <0.001
PAP levels (mm Hg) (N=4,649) 55±18 39±15 <0.001
RV diameter (cm) (N=1,314) 3.9±1.2 3.0±0.7 <0.001
TAPSE (cm) (N=1,590) 1.8±0.8 2.1±0.9 <0.001
Bpm: Beats per Minute; PAP: Pulmonary Artery Pressure Levels; TAPSE: Tricuspid Annular Plane Systolic Excursion; RV: Right Ventricle
Table 1: Clinical characteristics and diagnostic tests of 7,677 normotensive patients with acute PE, according to the presence or absence of atrial dilatation on the echocardiogram.