| |
IPAH |
CTD |
PoPH |
CTEPH |
LHD |
| Subjects n |
15 |
8 |
18 |
14 |
19 |
| Age (yrs) |
48.3 ± 17.4 |
53.3 ± 20.1 |
48.9 ±8.3 |
68.711.2 |
67.8 ± 9.3 |
| Gender (M/F) |
2/13 |
0/9 |
11/7 |
6/8 |
5/14 |
| IMC (Kg/m2) |
25.8 ± 4,7 |
22.8 ± 2.5 |
30.3 ± 5.1 |
28.5 ± 5.2 |
30.4 ± 4.6 |
| FVC () |
91.9 ± 18.1 |
76.3 ± 32.7 |
104.2 ± 13.3 |
92.1 ± 21.4 |
87.1 ± 22 |
| FEV1() |
83.8 ± 23.7 |
73.9 ± 24.9 |
92.58 ± 13.6 |
83.4 ±26.2 |
80.5 ± 23.5 |
| DLCOc/VA |
73.6 ± 15.1 |
66.4 ± 13.3 |
65.7 ±15.7 |
85.9 ±28.5 |
89.1 ± 16.6 |
| WHO FC () |
|
|
|
|
|
| I-II |
26.7 |
37.5 |
61.1 |
21.4 |
31.3 |
| III-IV |
73.3 |
62.5 |
38.9 |
78.5 |
68.7 |
| 6MWT, m |
401 ± 141.6 |
316.7 ± 81.1 |
462.4 ±110.2 |
302.8 ± 128.4 |
330.2±93 |
| proBNP |
2401.1 ± 3025.4 |
1246.1 ± 1450.5 |
695.1 ± 1216.9 |
2209.4 ± 3088.0 |
2523.1 ± 1777.8 |
| EchocardiographysPAP |
81.6 ± 82.7 |
67.6 ± 33.8 |
75.2 ± 25.2 |
70.7 ± 14 |
66.3 ± 15.5 |
| Haemodynamics |
|
| sPAP (mmHg) |
71±22.6 |
61±21.7 |
70.7±21.7 |
69.5±19.6 |
59.7±16.2 |
| dPAP (mmHg) |
34,7±12.5 |
29.3±8.5 |
30.6±10.17 |
25.9±8.4 |
23.5±4.2 |
| mPAP (mmHg) |
47.6 ± 15.2 |
40.8 ± 14.5 |
46.7± 14.5 |
43.5 ±12.7 |
39 ± 9.4 |
| PCWP, mmHg |
10.4±3.8 |
12.4±3.2 |
19.7±6.7 |
14.5±7.3 |
21.2±8.4 |
| TPG, mmHg |
30.3±14.2 |
28.6±13.2 |
26.1±14.9 |
23.6±11.5 |
17.2±6.9 |
| DPD, mmHg |
19.2±10.8 |
14±8.4 |
10.8±11.1 |
12.4±9.2 |
4,7±4.9 |
| CO (l.min-1) |
4.8 ±1.8 |
3.1 ± 2.5 |
5.8 ± 2.4 |
4.1±1.5 |
4.6 ± 1.9 |
| CI (l. min-1.m2) |
2.6 ± 1.2 |
1.9 ±1.9 |
3.1 ± 1.3 |
2.2 ± 0.8 |
2.5 ± 1.1 |
| PVR (din.seg.cm-5) |
656.3 ± 416.3 |
418.151.5 ± 151.1 |
425.1 ±323.1 |
515.4±3.1 |
287.6 ±141.6 |
|
| Values are shown as the mean ± SD. Abbreviations: IPAH (idiopathic PAH), CTD (connective tissue disease), PoPH (portopulmonary hypertension), LHD (left heart disease), WHO (World Health Organization), FC (functional class), 6MWT (6-minute walking test), sPAP (systolic pulmonary artery pressure), dPAP (diastolic pulmonary artery pressure), mPAP (mean pulmonary artery pressure), PCWP, mmHg (pulmonary capillary wedge pressure), TGP (transpulmonary gradient), DPD (diastolic pressure difference), CO (cardiac output), CI (cardiac index), PVR (pulmonary vascular resistance). |
