All patients BMI<25 BMI 25-34.9
Number 21 5 16
EBC
Arginine (nM) 25.80 (21.00) 19.40 (20.00) 25.85 (24.07)
ADMA (nM) 1.33 (1.43) 2.20 (0a) 1.17 (1.27)
SDMA (nM) 1.69 (0.86) 1.70 (0.30) 1.68 (0.29)
Nitrite (mcM) 0.20 (0.96) 1.11 (1.05) 0.15 (0.58)
Nitrate (mcM) 0.62 (1.09) 1.54 (1.48) 0.54 (0.53)*
Plasma
Arginine (mcM) 110.10 (21.60) 115.05 (11.53) 104.05 (27.70)
ADMA (mcM) 0.68 (0.13) 0.59 (0.22) 0.70 (0.12)
SDMA (mcM) 0.88 (0.38) 0.75 (0.29) 0.91 (0.39)
Nitrite (mcM) 0.45 (0.48) 0.43 (0.15) 0.61 (0.67)
Nitrate (mcM) 23.30 (26.04) 24.92 (27.80) 22.99 (21.81)
EBC/Plasma
Arginine (x10-3) 0.26 (0.16) 0.22 (0.20) 0.27 (0.21)
ADMA (x10-3) 1.77 (1.61) 2.82 (0a) 1.52 (1.62)
SDMA (x10-3) 1.95 (0.95) 2.33 (0.85) 1.86 (0.83)
Nitrite (mcM/mcM) 0.22 (2.77) 2.07 (3.05) 0.15 (2.60)
Nitrate (mcM/mcM) 0.03 (0.03) 0.04 (0.07) 0.02 (0.02)
(aOnly 1 EBC sample with a detectable measurement)
Table 2. Concentrations of measured metabolites in the EBC and plasma samples of study patients. Values represent median (interquartile range). Logarithmically transformed values were used for statistical analysis by ANOVA with Bonferroni post-hoc tests for paired comparisons. (*p<0.05 compared to BMI<25).