Attribute 1 2 3 4 Relative Importance to Attribute* Maintenance treatment Utilities Only short acting bronchodilator -0.6 Only long acting bronchodilator  0.2 Corticosteroid plus long acting bronchodilatator in combi inhalers 0.5 Corticosteroid plus long acting bronchodilatator in saperate inhalers -0.1 7.4 Reliever inhaler Utilities Separate inhaler -0.1 Same as maintenance 0.1     1.3 Time to onset, reliever Utilities Within 3 minute 0.6 10-15 minute -0.6     8.4 Duration of reliever Utilities 3-6 hour -0.6 12 hour 0.6     7.6 Symptom free days per mounth Utilities <10 days -4.4 10-14 days -1.9 15-20 days 1.9 >20 days 4.5 56.3 Treatment cots (TL) Utilities 20 1.6 40 -0.09 60 -0.1 80 -1.3 18.7

*The difference in utility between the level with the highest utility and the level with the lowest utility for each attribute.

Table 4: Utilities from a single hypothetical patient based on average in the study population.