Inpatient group
(n=172)
Outpatient group
(n=55)
P-value Total
(n=227)
Sex Male 132 (77%) 42 (76%) 0.954 174 (77%)
Age Mean in years (±SD) 57.3 (±7.6) 57.8 (±8.3) 0.655 57.4 (±7.8)
Tobacco Status Current smoker 91 (53%) 15 (31%) 0.005 106 (48%)
Former and never smoker 80 (47%) 34 (69%) 114 (52%)
Missing 1 6+   7
Size Mean in cm(±SD) 170 (±9) 169 (±6) 0.711 170 (±8)
Missing 1 1   2
Weight at diagnosis Mean in Kg (±SD) 69 (±13) 69 (±11) 0.708 69 (±13)
Missing 3 5   8
Histologic subtype Adenocarcinoma 102 (60%) 30 (54%) 0.695 132 (58%)
Squamous cell carcinoma 40 (23%) 13 (24%) 53 (24%)
Other 29 (17%) 12 (22%) 41 (18%)
Missing 1     1
Disease stage Stage I to IIIA 27 (16%) 11 (20%) 0.468 38 (17%)
Stage IIIB and IV 144 (84%) 44 (80%) 188 (83%)
Missing 1     1
Performance status PS 0 to 1 159 (95%) 47 (94%) 0.547 206 (95%)
PS 2 9 (5%) 3 (6%) 12 (5%)
Missing 4 5   9
Chemotherapy doublet drug Docetaxel 2 (1%) 30 (54%) <0.0001 32 (14%)
Gemcitabine 79 (46%) 19 (35%) 98 (43%)
Pemetrexed 24 (14%) 5 (9%) 29 (13%)
Vepeside 1 (1%) - 1 (1%)
Vinorelbine 65 (38%) 1 (2%) 66 (29%)
Bevacizumab 10 (6%) 0 0.124 10 (4.4%)
Scheme with day-8 142 (83%) 20 (36%) <0.0001 162 (72%)
Missing 1 -   1
Thoracic radiotherapy Yes 37 (25%) 11 (22%) 0.702 48 (24%)
Missing 22 5   27
Cisplatin planned delivery dose Median in mg/m² (±IQR) - 80 (±0) 75 (±5) <0.0001 80 (±5)
Missing 7 3   10
Cisplatin delivered courses (n=226) Median ±IQR 4 (±3) 4 (±2) 0.065 4 (±3)
Missing        
Relevant comorbiditiesa At least one 47 (27%) 12 (22%) 0.405 59 (26%)
Missing 1     1
Concomitant use of nephrotoxic drugsb At least one 34 (20%) 4 (7%) 0.03 38 (17%)
Missing 1     1
Table 1: Main characteristics of the population included in the study.