Surfactant Preparation Phospholipids (mg/mL) DSPC (mg/mL) Total Proteins (mg/mL) SP-B (mg/mL) PLMGN (mol% total PL)
Poractant alfa (Curosurf)1 Minced porcine lung extract – purified via Liquid Gel Chromatography 76 30 1 0.45 3.8 + 0.1
Beractant (Survanta)2 Minced bovine lung extract/ DPPC, Palmitic Acid, Tripalmitin 25 11-15.5 <1 Not specified 1.5 + 0.2
Calfactant® (Infasurf)3 Bovine Lung Lavage/DPPC, Cholesterol 35 16 0.7 0.26 Not specified
DSPC-disaturatedphosphatidylcholine, SP-B-surfactant protein B, SP-C-surfactant associated protein-C, PLMGN-plasmalogens
Table 2: Composition of animal derived surfactants.