Outcome Measure Percentage Change: P Value* vs Placebo
Overall Low Medium High
Peak VO2 0.02 0.44 0.03 0.02
Mean PAP 0.01  1.0 0.01 0.01
PVRI 0.001 0.37 0.06 0.0001
Cardiac index 0.14 0.27 0.30 0.07
PAP=pulmonary arterial pressure; PVRI=pulmonary vascular resistance index;
VO2=oxygen consumption.
*Values are rounded, with those ≤0.05 in bold face.
Table 3: Descriptive P Values (Active Treatment vs. Placebo) for Cumulative
Distribution Functions: Percentage Change from Baseline.