Outcome Measure
Percentage Change:
P
Value
*
vs Placebo
Overall
Low
Medium
High
Peak VO
2
0.02
0.44
0.03
0.02
Mean PAP
0.01
1.0
0.01
0.01
PVRI
0.001
0.37
0.06
0.0001
Cardiac index
0.14
0.27
0.30
0.07
PAP=pulmonary arterial pressure; PVRI=pulmonary vascular resistance index;
VO
2
=oxygen consumption.
*
Values are rounded, with those ≤0.05 in bold face.
Table 3:
Descriptive P Values (Active Treatment vs. Placebo) for Cumulative
Distribution Functions: Percentage Change from Baseline.