| Wistar Rat |
SP (mmHg) |
DP (mmHg) |
MAP (mmHg) |
| Before |
144.5 ± 0.4 |
101.4 ± 0.3 |
131.1 ± 0.5 |
| LASSBio-1366 |
139.8 ± 0.6 |
102.8 ± 0.7 |
129.9 ± 0.7 |
| 5 min after |
141.0 ± 0.2 |
99.2 ± 0.4 |
128.0 ± 1.2 |
| 10 min after |
143.0 ± 0.4 |
104.2 ± 0.3 |
125.0 ± 1.0 |
| 20 min after |
141.0 ± 0.4 |
98.9 ± 0.5 |
130.0 ± 0.9 |
aAll values are mean ± SEM, n=6 per group
bSP: Systolic Pressure; DP: Diastolic Pressure; MAP: Mean Arterial Pressure |
