HLA Allele Controls n = 524 LTI n = 218 PTB n = 318 Controls vs PTB LTI vs PTB
HLA-DRB1* n (%) n (%) n (%) Pa OR 95%CI P OR 95%CI
01 68 (12.98) 23 (10.55) 43 (13.52)            
03 52 (9.92) 19 (8.72) 37 (11.64)            
04 62 (11.83) 31 (14.22) 55 (17.30) 0.0374 1.55 1.04-2.29      
07 103 (19.66) 46 (21.10) 44 (13.84) 0.036 0.65 0.44-0.96 0.034 0.6 0.38-0.94
08 19 (3.63) 15 (6.88) 13 (4.09)            
09 5 (0.95) 2 (0.92) 2 (0.63)            
10 6 (1.14) 3 (1.32) 4 (1.26)            
11 49 (935) 20 (9.17) 31 (9.75)            
12 6 (1.14) 0 (0.0) 4 (1.26)            
13 74 (14.12) 22 10.09) 34 (10.69)            
14 10 (1.91) 8 (3.67) 11 (3.46)            
15 62 (11.83) 26 35 (11.01)            
16 8 (1.52) 3 (1.32) 7 (2.20)            
aUncorrected p value. After Bonferroni correction for multiple comparisons p values were not significant
No significant differences were obtained when we compared between the other groups. One PTB patient could not be HLA typed and for this reason in all the tables n is 318 instead 320.
Table 4: Distribution of HLA-DRB1* allele frequencies in controls, individuals with LTI and PTB patients.