| Grouping |
Drugs |
Group 1
First-line oral agents |
Isoniazid (H)
Rifampicin (R)
Ethambutol (E)
Pyrazinamide (Z)
Rifabutin (Rfb)a |
Group 2
Injectable agents |
Kanamycin (Km)
Amikacin (Am)
Capreomycin (Cm)
Viomycin (Vm)
Streptomycin (S) |
Group 3
Fluoroquinolones |
Moxifloxacin (Mfx)
Levofloxacin (Lfx)
Ofloxacin (Ofx) |
Group 4
Oral bacteriostatic second-line
Agents |
Ethionamide (Eto)
Protionamide (Pto)
Cycloserine (Cs)
Terizidone (Trd)
p-aminosalicylic acid (PAS) |
Group 5
Agents with unclear role in MDR-TB
treatment (not recommended by WHO) |
Clofazimine (Cfz)
linezolid (Lzd)
Amoxicillin/clavulanate (Amx/Clv)
Thioacetazone (Thz)
Imipenem/cilastatin (Ipm/Cln)
High-dose isoniazid (high dose H)b
Clarithromycin (Clr) |
