Figure 3: Calcified granulomatous lesions exhibited minimum inflammation but contained a considerable amount of bacterial genomes.
(A) Real-time PCR quantifications for M. tuberculosis were expressed by boxplots with logarithmic scale. (B-F) Histologic quantification of inflammation in granulomas based on the measurements of the mean numbers of lymphocytes (B), neutrophils (C), mean thickness of the epithelioid cell layer (D), and the number of multinucleated giant cells (E) in each lesion of the three groups. Results are expressed by boxplots. (F) Sizes of granulomas are expressed by boxplots with a logarithmic scale. n=10 in the ZN(+), 13 in the Cal(-), 11 in the Cal(+). * P<0.05, Steel-Dwass test.