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Figure 4: Pathway for the synthesis of the MGLP in M. tuberculosis. Confirmed activities are shaded in green. White boxes indicate putative/deduced enzyme activities. Genes linked to the MGLP pathway by mutagenesis studies are indicated in blue box. GpgS (Rv1208), glucosyl-3-phosphoglycerate synthase; GpgP (Rv2419), glucosyl-3-phosphoglycerate phosphatase; DggS, diglucosylglycerate synthase; GT, glucosyltransferases |