Figure 5: Number of viable bacteria (CFU/mL) at necropsy in lung and spleen tissues after bacterial challenge of guinea pigs immunized with different rAg85 formulations by different routes: PLGA-TDB-AG85 = microparticles containing rAg85B and trehalose dibehenate as adjuvant; PLGA-AG85 = microparticles containing rAg85B; BCG = BCG solution. Microparticles were administered by the pulmonary route and BCG was administered subcutaneously. (average ± std deviation, n=6).