First consultation

Second consultation

Third consultation

 

Lifestyle

Lifestyle + PPI

Lifestyle + PPI
+ Alginate

Lifestyle

Lifestyle + PPI

Lifestyle + PPI + Alginate

Lifestyle

Lifestyle + PPI

Lifestyle + PPI + Alginate

Oedema of the inter-arytenoid region

Number of patients

Number of patients

Number of patients

Grade 1 (normal)

0

0

0

9

8

11

13

13

13

Grade 2

35

29

35

35

29

40

23

21

28

Grade 3

34

33

41

18

17

19

9

9

13

Grade 4

8

8

13

3

2

0

1

0

0

Grade 5 (totally closed)

1

0

0

0

0

0

0

0

0

N

78

70

89

65

56

70

46

43

54

Mean grade

2.68

2.70

2.75

2.23

2.23

2.11

1.96

1.91

2.00

SD

0.712

0.667

0.695

0.745

0.738

0.649

0.759

0.718

0.700

Range

2-5

2-4

2-4

1-4

1-4

1-3

1-4

1-3

1-3

Difference to Lifestyle treatment (LS) means [95% CI1]

 

 

 

 

-0.03
[-0.25; 0.20]

-0.14
[-0.35; 0.07]

 

 

 

p value2

 

 

 

 

0.81

0.20

 

 

 
1Confidence interval
2Two sided test comparison to Lifestyle treatment group in a statistical model including baseline as covariate and treatment group as fixed effect.
Table 3: The 5 inter-arytenoid grades summary and analysis.