Figure 8: A: Experimental set up for recording membrane potential of the pyramidal neuron in slice preparation from a ratís AI. B: Schematic diagram of responses. Evoked potential comprised, at maximum, 4 phases in the following order: (1) fast depolarization, (2) fast hyperpolarization, (3) slow depolarization then (4) slow hyperpolarization (solid curves in red [depolarization] or blue [hyperpolarization]). Current injection procedure in combination with pharmacological manipulation revealed that these components were mediated chiefly through (1) AMPA-receptor mediated excitatory post-synaptic potentials (EPSP), (2) GABAA-receptor mediated inhibitory post-synaptic potentials (IPSP), (3) NMDA-receptor mediated EPSP and (4) GABAB-receptor mediated IPSP, respectively (broken curves) (Cox et al. [69]).