Variables Training sample Validation sample p value
No. of patients 361 102  
Age, years (mean, SD) 71.43 (8.68) 70.39 (8.17) NS
PSA, ng/mL (median, IQR) 253.8 (728.3-1349.7) 358.0 (652.0-1597.2) NS
≤ T3, T4 (%) 81.1, 18.9 62.8, 37.2 <0.0001
EOD 1, 2, 3, 4 (%) 40.7, 26.6, 25.5, 7.2 35.3, 27.5, 28.4, 8.8 NS
Gleason ≤ 6, 7, 8-10 (%) 6.4, 18.6, 75.0 3.0, 16.7, 80.3 NS
Use of docetaxel (%) 19.1 35.3 <0.0001
Observation period, years (median, IQR) 3.11 (3.11-4.15) 2.58 (2.58-3.51) 0.027
SD: Standard deviation
IQR: Interquartile range
EOD: Extent of disease on bone scan
Table 1: Baseline characteristics of training and validation sample.