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Figure 3: Effect of thiazolidinone derivate on the multiplication of intracellular T. cruzi. (a) Vero cells infected with T. cruzi. (b) Vero cells treated with 1 mM of compound for 24 h. (c) After incubation very few cells were infected with T. cruzi. (d) Intracellular amastigotes had undergone several processes of disorganization (black arrow) leading to their elimination. White arrows: nucleus. Scale bars: A and B: 100 μm, C and D: 10 μm. |