Table 2 |
Summary of calibration curves for topiramate with backcalulated concentrations |
Linearity |
Topiramate, concentration in ng/ml |
CS-1 |
CS-2 |
CS-3 |
CS-4 |
CS-5 |
CS-6 |
CS-7 |
CS-8 |
CS-9 |
10 |
20 |
200 |
400 |
800 |
1600 |
2400 |
3200 |
4200 |
1 |
10.010 |
20.542 |
200.010 |
400.254 |
800.277 |
1623.210 |
2425.210 |
3254.354 |
4,245.550 |
2 |
10.254 |
20.005 |
213.214 |
394.521 |
789.351 |
1652.012 |
2435.021 |
3215.221 |
4,221.584 |
3 |
11.001 |
21.254 |
198.542 |
420.124 |
812.254 |
1623.120 |
2432.214 |
3200.124 |
4,121.897 |
4 |
9.854 |
20.023 |
197.586 |
398.542 |
800.001 |
1599.257 |
2465.263 |
3242.214 |
4,212.541 |
5 |
10.005 |
19.258 |
200.012 |
400.235 |
789.210 |
1624.258 |
2432.123 |
3245.125 |
4,255.654 |
Mean |
10.225 |
20.216 |
201.873 |
402.735 |
798.219 |
1624.371 |
2437.966 |
3231.408 |
4211.445 |
% Nominal conc. |
102.25 |
101.08 |
100.94 |
100.68 |
99.78 |
101.52 |
101.58 |
100.98 |
100.27 |
SD |
0.457 |
0.739 |
6.423 |
9.998 |
9.542 |
18.693 |
15.682 |
22.760 |
53.010 |
%CV |
4.47 |
3.65 |
3.18 |
2.48 |
1.20 |
1.15 |
0.64 |
0.70 |
1.26 |
CS = Calibration Standard |
|
| Conc. = Concentration |
|
