Sample Endothermal Peak
(Onset temp.,°c)
Energy (- j/g)
DSPC powder 52.44 0.13
DSPG powder 57.45 0.72
Cholesterol powder 143.09 56.26
Empty liposomes suspension 88.58 1523.19
Alendronate powder 118.49, 259.37 415.08, 24.41
Alendronate solution 85.44 1542.88
Empty liposomes spiked with
alendronate solution
76.98 1504.90
Liposomal alendronate suspension 90.54 1556.31
Table 1: Differential scanning calorimetry analyses of liposomal alendronate and of the formulation ingredients.
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