Helminths Effect of infection or injection Ref.
Nematode    
Ancylostoma caninum Inhibition of TNBS-induced colitis in mice by injecting A. caninum antigens [9]
Ascaris suum Chronic infection reduces eye disease in mice [10]

Trichinella spiralis

Prevention of colitis in C57BL/6 mice [11]

Strongyloides stercoralis

Suppression of pulmonary allergy in BALB/c mice [12]
Heligmosomoides polygyrus Inhibition of autoimmune type 1 diabetes in NOD mice [13]
Protection from colitis in C57BL/6 [27,28]
Platyhelminth    
Schistosoma mansoni     Inhibition of TNBS-induced colitis in mice by injecting S. mansoni antigens [9]
Inhibition of autoimmune type 1 diabetes in NOD mice [13]
Inhibition of type 1 diabetes in NOD mice by injecting S. mansoni antigens [14]
Prevention of DSS-induced colitis in BALB/c mice [15]
Suppression of collagen-induced arthritis in mice [16]
Schistosoma japonicum   Inhibition of asthma development in BALB/c mice by injecting the egg antigens   [17]
Protective effects for arthritis in DBA/1 mice [18]
DSS, dextran sodium sulphate; NOD, Non-obese diabetic; DNBS, dinitrobenzene sulfonic acid; TNBS, trinitrobenzene sulfonic acid
Table 1: Examples of helminth parasites in animal models for inflammatory and autoimmune disease therapy.
Goto home»