Study groups GG vs. AA GA vs. AA GG/GA vs. AA GG vs. GA/AA
N* OR (95% CI) P OR (95% CI) P OR (95% CI) P OR (95% CI) P
Total 17 1.21(1.12-1.60) ‡ <0.001 1.06(0.99-1.36) 0.536 1.16 (1.03-1.46) ‡ <0.001 1.12 ( 0.95-1.31)‡ <0.001
Cancer type                  
Hepatocellular 1 1.43(1.10-1.87) 0.851 1.29(0.99-1.68) 0.771 1.36(0.92-1.75) 0.796 1.17 (0.96-1.37) 0.920
Gastric 6 1.22 (1.02-1.46) 0.523 1.82 (1.16-2.87) 0.704 1.13 (1.01-1.26) 0.711 1.25(1.06-2.39) 0.642
Colorectal 7 1.13 (1.01-1.26)‡ 0.020 0.805(0.50-1.30)‡ 0.006 0.86 (0.54-1.35)‡ 0.006 1.08(0.80- 1.45) 0.215
Esophagus 2 1.00(0.24-4.30)‡ <0.001 1.45(1.11-1.91) 0.146 1.19(0.48-2.96)‡ 0.002 0.81(0.27-2.39)‡ <0.001
Oral 1 0.73 (0.38-1.39) 0.312 1.09 (0.26-4.55)‡ 0.013 1.012(0.30-3.45)‡ 0.026 0.88(0.56-1.36) 0.478
Ethnicity                  
Asian 12 1.40(1.12- 1.69)‡ <0.001 1.26(1.02- 1.51)‡ <0.001 1.18 (1.08-1.55)‡ <0.001 1.14(0.96-1.36)‡ <0.001
European 5 1.13(0.60-1.97)‡ 0.070 0.98 (0.69-1.37)‡ 0.070 1.11(0.76-1.52)‡ 0.029 1.01(0.73 -1.51) 0.154
Source of Control                  
Population-based 5 1.19(0.91-1.90)‡ <0.001 1.16 (1.08-1.50)‡ 0.029 1.10(1.01-1.72)‡ <0.001 0.95 (0.68-1.73)‡ <0.001
Hospital-based 12 1.25(1.01 -1.74)‡ 0.001 1.15( 0.88-1.50)‡ <0.001 1.14(0.84-1.54)‡ <0.001 0.97 (0.82 -1.39) 0.150
Abbreviations: CI, confidence interval; OR, odds ratio. * Studies of comparison,﹩P-value of Q-test for heterogeneity test, ‡ Random model was used.
Table 2: Results of meta-analysis for MMP-7 (-181A>G) polymorphism and digestive cancer risks.
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