Parameters

Test

Reference

P valueψ

90 %CIφ
(80-125 %)

T/R ratio

Cmax (µg/ml)

10.058±0.318

10.398±0.258

0.21

98.72-102.16

96.47

Tmax (h)

1.42±0.164

1.38±0.065

0.89

 

 

Kele (l/hr)

0.274±0.028

0.255±0.028

0.50

T1/2 (h)

2.862±0.311

3.093±0.318

0.50

AUC0-t (µg.h/ml)

49.09±2.63

50.603±2.725

0.44

101.23-103.33

97.15

AUC0-inf  (µg.h/ml)

50.925±2.77

53.584±2.94

0.20

101.18-104.64

95.16

Table 4b: Pharmacokinetic Parameters after Single Oral Dose of 600 mg Amtolmetin Guacil Tablet in 12 Healthy Male Volunteers. Pharmacokinetic Parameters of Tolmetin Glycinamide
Goto home»