Pharmacokinetic Parameters Test (T) Reference (R) T/R I C 90% for Mean Ratio**
Mean* SD Mean* SD
Tmax (h) 1.82 0.81 1.54 0.75 - -
Cmax (ng/mL) 879.30 345.00 884.30 501.10 106.84% 93.63% - 121.92%
Kel 0.24 0.14 0.24 0.12 - -
T1/2 (h) 4.70 5.36 3.86 2.70 - -
AUC0-t (ng.h/mL) 2137.70 795.40 2107.30 1058.50 105.83% 96.80% - 115.72%
AUC0-∞ (ng.h/mL) 2233.80 768.70 2183.00 1061.00 107.52% 98.45% - 117.43%
* Arithmetic mean; ** Geometric mean; IC = Confidence intervals; SD = Standard deviation
Table 3: Pharmacokinetic parameters obtained after study using single dose of 40mg furosemide tablets.
Goto home»