Table 2

Influenza A virus—genomic segments and coding
RNA segment	Designation	Known and probable functions
segment1	PB2	Cap binding subunit, polymerase, virulence determinant
segment2	PB1	Catalytic subunit of RNA polymerase
segment3	PA	Subunit, viral RNA polymerase
segment4	HA or hemagglutinin	Receptor binding; membrane fusion of cell and virus to bring about infection
segment5	NP or nucleocapsid protein	Nucleoprotein (capsid) and viral synthesis
segment6	NA	Cleavescellular neuraminic acid prevents virus aggregation; facilitates release of newly produced virus
segment7	MP or M2or M1	Interacts with genome and nuclear export factor, assists viral assembly (M1).
segment7	MP or M2or M1	Tetramericion channel, controls pH in Golgi during HA synthesis and in virion uncoating (M2)
segment8	NS or NEP or NS1	Post-transcription RNAcontrol;interferon antagonist(NS1)
segment8	NS or NEP or NS1	Nuclear export of viral RNA, viral assembly(NEP)

Table 2: Influenza virus data classifications with RNA segmentation approach.