Figure 3: Best Docked confirmation of Dopamine and key residues with α2a-, α2b- and α2c- ARs. Structural models for the human α2- adrenoceptors were constructed based on homology with Human dopamine D3 structure (see Methods). Dopamine was positioned based on key amino-acid contacts identified in Peltonen et al. (2004) D( 3.32), S(5.46) and S(5.42).