Rank Pathway Name Impact Factor #Input Genes in Pathway Rank Pathway Name Impact Factor #Input Genes in Pathway
1 Long-term depression 4.333 2 21 Melanoma 1.87 1
2 Ribosome 4.185 2 22 Long-term potentiation 1.87 1
3 Gap junction 3.902 2 23 VEGF signaling pathway 1.857 1
4 GnRH signaling pathway 3.785 2 24 Cardiac muscle contraction 1.832 1
5 Insulin signaling pathway 3.202 2 25 Chronic myeloid leukemia 1.819 1
6 Alzheimer's disease 2.911 2 26 Fc epsilon RI signaling pathway 1.807 1
7 Huntington's disease 2.793 2 27 Adherens junction 1.807 1
8 Thyroid cancer 2.717 1 28 ErbB signaling pathway 1.684 1
9 Regulation of actin cytoskeleton 2.463 2 29 Prostate cancer 1.664 1
10 Proteasome 2.362 1 30 Toll-like receptor signaling pathway 1.559 1
11 Bladder cancer 2.362 1 31 Melanogenesis 1.551 1
12 Shigellosis 2.216 1 32 T cell receptor signaling pathway 1.5 1
13 Pathogenic Escherichia coli infection 2.216 1 33 Parkinson's disease 1.444 1
14 Endometrial cancer 2.16 1 34 Leukocyte transendothelial migration 1.444 1
15 Non-small cell lung cancer 2.124 1 35 Natural killer cell mediated cytotoxicity 1.35 1
16 Acute myeloid leukemia 2.073 1 36 Ubiquitin mediated proteolysis 1.33 1
17 Vibrio cholerae infection 2.026 1 37 Tight junction 1.324 1
18 Glioma 1.951 1 38 Calcium signaling pathway 1.082 1
19 p53 signaling pathway 1.909 1 39 Focal adhesion 0.979 1
20 Renal cell carcinoma 1.896 1 40 MAPK signaling pathway 0.76 1
21 Melanoma 1.87 1 41 Pathways in cancer 0.616 1
Table 9: KEGG pathway analysis of 57 common genes between gene clusters CI-Purple (M1) and MI-Black (M1) using the tool Pathway Express.