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Figure 3: Power curve of the naïve model (solid line) and the integrated model (dashed line) according to different simulation scenarios: sample size ranged from 20 to 300 and the protein intensities were located in the middle part of a sigmoidal curve. Detection powers (type I error if α2=0) denoted by p1 and p2 under different correlation strengths were report on the bottom of each plot for the naïve and integrated models, respectively. Both models can well control the pre-specified type-I error when sample size were bigger than 50. Two models had similar detection performance, especially when sample size increased. |