Tumors

Endocan Expression

Prognosis

Litterature

Breast

Endocan gene expression studies

Higher risk of metastasis

van 't Veer et al., 2002

Lung

Endocan gene expression studies

Endocan intratumor immunostaining & high levels of serum endocan

Bad prognosis signature

Seems to correlate with metastasis

Borczuk et al., 2004

Grigoriu et al., 2006

Brain

Endocan expression is increased in endothelial cells in high grade glioblastoma

High expression correlate to a shorter survival

Maurage et al., 2009

Ovary

Endocan gene expression studies

Bad prognosis signature

Buckanovich et al., 2007

Kidney

Endocan gene expression studies by microarrays

 

Endocan intratumor immunostaining and increase of circulating level of endocan

Bad prognosis signature

 

Renal clear cell carcinoma of poor prognosis

Amatschek et al., 2004 ; Lenburg et al., 2003, Cifola et al., 2008

Leroy et al., 2010

Liver

Microvascular density measured through endocan immunostaining (endocan-MVD)

Independent prognostic marker for overall survival

Huang et al., 2009

Table 1: Endocan expression in human tumors.