Toxicity

No.(%) of patients

GM-CSF

IFNa

IL-2

Toxicity grade

Rate (%)

Toxicity grade

Rate (%)

Toxicity grade

Rate (%)

Fever

32 (91.4)

1

5.7

1

43

1

17.1

2

25.7

Erythema in injection site

24 (68.6)

1

65.7

1

2.9

1

-

Hypotension

12 (34.3)

-

-

-

-

1

25.7

2

8.6

Anorexia

9 (25.7)

-

-

1

17.1

1

8.6

Nausea

8 (22.9)

-

-

1

14.3

1

8.6

Lymphopenia

7 (20)

-

-

-

-

1

20

Fatigue

6 (17.6)

1

2.9

1

11.4

1

2.9

Allergy

3 (8.6)

1

8.6

-

-

-

-

Insomnia

3 (8.6)

-

-

1

5.7

1

2.9