Figure 1: NBD peptide associated with a reduction in tumor-induced wasting in an experimental model of cancer cachexia. (A) The effects of NBD peptide (injected daily for 11 days) on carcass weight (g). (B) Mean final % weight loss of each of the five groups. (C) Using MRI for body composition analysis, NBD peptide was associated with a dose response increase in LBM and FM when compared to untreated tumor-bearing mice on day 17. (D) There were no significant differences in average daily food intake for each of the five groups. * p < 0.05. ** p < 0.001. |