Figure 6: PHO-S induced downregulation of Bax/Bad in B16F10 tumor cells. PHO-S 7 mg/Kg and 14 mg/Kg was able to induce apoptosis, and to decrease protein expression of Bad/Bax (P <0.001). The levels of Bcl-2 protein were not altered in relation to treated groups (inset). Values depict the mean an average (±SD) and are representative of three independent experiments.