Table 2

		MGMT Promoter Methylation Test			Microsatellite Instability Test
Sample	Tissue	*MGMT*	b-Actin	Result	*TGFBRII*	*D5S346*	*BAT26*	*BAT25*	*D17S250*	*D2S123*	Result
LNG3	IB adeno	407	6654	meth	Neg	Neg	Neg	Neg	Neg	Neg	MSIS
LNG39	IA adeno	18	1255	meth	Neg	Neg	Neg	Neg	Neg	Neg	MSIS
LNG66	IV adeno-br met	52	6014	meth	Neg	Neg	Neg	Neg	Neg	Neg	MSIS
LNG68	IV adeno-lung	661	9421	meth	Neg	Neg	Neg	Neg	Neg	Neg	MSIS
LNG72	IIIB squam	56	2935	meth	Neg	LOH	Neg	Neg	Neg	Neg	MSIS
LNG75	IB adeno	85	4716	meth	Neg	Neg	Neg	Neg	Neg	Neg	MSIS
LNG79	IV adeno-ln	56	3526	meth	Neg	Neg	Neg	Neg	Neg	Neg	MSIS
LNG97	IIA squam	281	29547	meth	Neg	LOH	Neg	Neg	Neg	Neg	MSIS
LNG109	IB NSCLC	897	5431	meth	Neg	Neg	Neg	Neg	Neg	Neg	MSIS
LNG40	IIIB large cell	<10	1994	unmeth	Neg	Neg	Neg	MSI	Neg	Neg	MSIL
LNG48	IIB large cell	<10	6607	unmeth	Neg	MSI	Neg	Neg	Neg	Neg	MSIL
LNG63	IIIA squam	<10	781	unmeth	Neg	MSI	Neg	Neg	MSI	Neg	MSIH
LNG67	IA adeno	<10	4971	unmeth	Neg	Neg	MSI	Neg	MSI	Neg	MSIH

Table 2 : MGMT promoter methylation and MSI test results. The results of the MGMT promoter methylation test and the Microsatellite instability test are shown for the 13 tumor samples that displayed defects in either of these two repair mechanisms. The first column indicates the patient sample ID and the second column indicates the tumor stage and histology of each sample. The copy number of the MGMT promoter amplicon is shown on the third column, while the copy number of the reference, β-Actin, amplicon in shown on the fourth column. The fifth column indicates whether the sample was categorized as having the MGMT promoter region methylated or unmethylated. Columns 6-11 show the instability of 6 microsatellite regions. Negative (Neg) indicates stable regions, MSI indicates regions that displayed instability, and LOH indicates regions with loss of heterozygosity. The last column indicates whether a sample was categorized as MSI-stable (MSIS) or samples with no regions of instability, MSI-high (MSIH) or samples were 2 loci or more exhibited microsatellite instability, or MSI-low(MSIL) or samples were 1 loci exhibited microsatellite instability.