Table 2

Groups	Power of cardiac contractility (gm)	Heart rate (bpm)
control saline	3.778±0.7104	326.2±18.59
control carvedilol	2.579±0.4133	231.3±19.04
control nebivolol	2.658±0.3995	235.7±14.94
doxorubicin alone*	1.433±0.2861	75.33±12.09
dox + carvedilol†	2.170±0.2445	258.5±28.06
dox + nebivolol‡§	2.071±0.2263	250.3±29.93

*All measures of dox alone group was significantly different compared to control groups p<0.0001 † Cardiac contractility and heart rate were significantly different in dox-carvedilol treated group compared dox alone group p= 0.0001 & <0.0001 respectively ‡ dox–nebivolol treated group showed significant difference in cardiac contractility and heart rate compared to dox alone group p =0.0002 &<0.0001 respectively § No significant difference between measures of dox-nebivolol and dox-carvedilol treated groups p>0.05

Table 2: Cardio dynamic Measurements in Langendorff-perfused rat hearts. Data are presented as mean � S.D. (n=8).