*All measures of dox alone group was significantly different compared to control groups p<0.0001
† Cardiac contractility and heart rate were significantly different in dox-carvedilol treated group compared dox alone group p= 0.0001 & <0.0001 respectively
‡ dox–nebivolol treated group showed significant difference in cardiac contractility and heart rate compared to dox alone group p =0.0002 &<0.0001 respectively
§ No significant difference between measures of dox-nebivolol and dox-carvedilol treated groups p>0.05
Table 2: Cardio dynamic Measurements in Langendorff-perfused rat hearts. Data are presented as mean ± S.D. (n=8).