CAS/NIST

COMPOUND

%TIC in M

%TIC  in S

RATIO M/S

117-84-0

1,2-Benzenedicarboxylic acid, diisooctyl ester

1.03

0.61

1.68

36653-82-4

1-Hexadecanol*

3.29

0.09

35.90

83834-59-7

2-Ethylhexyl trans-4-methoxycinnamate

1.02

0.78

1.31

108-67-8

Benzene, 1,3,5-trimethyl*

0.12

0.03

3.41

75-43-4

Dichlorodifluoromethane

0.03

0.01

1.80

112-40-3

Dodecane*

0.13

0.11

1.27

77422-34-5

N-Morpholinomethyl-isopropyl-sulfide

0.32

0.23

1.37

124-19-6

Nonanal#

0.30

0.11

2.79

17301-32-5

Undecane, 4,7-dimethyl

0.17

0.11

1.54
Table 2: Compounds that showed =100% enrichment in melanoma compared to the healthy matched skin sample are listed together with the % Total Ion Count, (%TIC) and their ratio in Melanoma (M) vs Skin (S) - M/S. In order to compensate for differences, the signal intensity of each volatile compound was normalized to the TIC of all volatiles detected in the particular sample. Compounds in bold have been previously identified as significantly different in melanoma when compared to nevi (*) or to skin (#) control [9].