| Cell line |
NCIH929 |
MM.1S |
U266 |
| Tissue |
Bone marrow |
Peripheral blood |
Peripheral blood |
| Cell type |
B lymphocyte
IgA kappa |
B lymphocyte
IgA lambda |
B lymphocyte
IgE lambda |
| Positive for |
PCA1
Transferrin receptor
CD38 |
PCA1
HLA-DR
CD38, CD59; CD52
ILR2 |
|
| Unique characteristics |
NRas active;
Amplified c-Myc;
Overexpression of t(4;14) and FGFR3 |
c-Maf over-expression;
Sensitive to dexamethasone |
Produces IL-6;
High STAT3 levels;
Resistant to Fas |
Data are according to ATCC.
Ig, immunoglobulin; PCA1, plasma cell-associated antigen; HLA-DR, D-related
human leukocyte antigen; FGFR3, fibroblast growth factor receptor 3; IL-6,
interleukin 6; STAT3, signal transducers and activators of transcription 3 |