Molecular studies ALK gene rearrangement Clathrin/ALK Nucleophosmin/ALK Other rearrangements IgH gene rearrangement 25 20 25 19 4 2 17 100 76 16 8 85 IgH – immunoglobulin heavy chain

Table 4: Genetic feature of investigated cases of ALK+ LBCL reported in the literature.