Factor Number of Patients1(n=212) 3-Yrs Recurrence-Free 5-Yrs Disease-Free Survival
% (95% CI) P Value2 % (95% CI) P Value

Race

    0.8354   0.7082
Black 4 NA3   NA3  
White 208 88 (83- 92)   98 (96- 100)  

Age at diagnosis (years)

    0.8123   0.1935
60-70 104 85 (78- 92)   NA3  
<=60 86 89 (83- 96)   97 (93-100)  
>70 22 81 (65- 98)   NA3  

Pre-prostatectomy PSA (ng/ml)

    0.0434   0.6713
4-10 113 88 (82- 94)   97 (93- 100)  
<4 22 NA3   NA3  
>10 43 84 (72- 95)   96 (87- 100)  

Gleason score

    <0.001   <0.001
2-6 130 94 (89- 98)   NA3  
7 70 77 (67- 87)   98 (93- 100)  
8-10 12 67 (40- 93)   71 (43- 100)  

Surgical margin

    <0.001   0.3690
Negative 133 95 (91- 98)   99 (96- 100)  
Positive 78 74 (64- 84)   95 (90- 100)  

Extracapsular extension

    <0.001   0.2664
Negative 125 93 (88- 97)   99 (96- 100)  
Positive 67 76 (65- 86)   94 (88- 100)  

Disease Stage

    <0.001   0.1248
Localized (T1) 8 71 (38-100)   NA3  
Localized (T2) 134 94 (90- 98)   99 (96- 100)  
Localized (T3) 57 71 (59- 83)   95 (89- 100)  

AURKA SNP rs1468055

    0.7213   0.3282
A/A 17 76 (57- 100)   NA3  
A/C 53 84 (74- 94)   97 (91- 100)  
C/C 124 88 (83- 94)   98 (95- 100)  

AURKA SNP rs8117896

    0.5140   0.1909
C/C 70 87 (79- 85)   96 (91- 100)  
C/T 42 82 (70- 94)   NA3  
T/T 34 88 (77- 99)   NA3  

AURKA SNP rs2064863

    0.0714   0.4111
G/G 74 83 (75- 92)   97 (92- 100)  
G/T 83 89 (82- 96)   97 (92- 100)  
T/T 43 88 (78- 98)   NA3  

AURKA SNP rs1468056

    0.4731   0.5014
C/C 29 73 (55- 90)   NA3  
C/G 53 89 (80- 97)   97 (92- 100)  
G/G 74 90 (83- 97)   NA3  
1Analysis were limited to patients for whom data were available. 2P values for each factor were calculated by the log-rank test. 3Unable to calculate because all recurrence or death events occurred before 3-y or 5-y, respectively.
Table 3: Effect of Patient Factors on Post-prostatectomy Outcomes, Univariate Analysis.