Figure 7: Effect of co-administration of mitomycin C and cisplatin with or without the administration of B. aristata on lipid peroxide level. The animals were divided into four groups of six animals each. Group-1, received saline, Group-2, received a single dose of mitomycin C (2 mg/kg body weight, i.p.) and cisplatin (12 mg/ kg body weight, i.p). Rats were sacrificed 48 h after the administration of drugs. Group-3, received alcoholic extract of B.aristata (10 mg/100g body weight, oral) for three days. Group-4 recieved alcoholic extract of B.aristata (10 mg/100 g body weight, oral) for three days, followed by single dose of mitomycin C (2 mg/kg body weight, i.p ) and cisplatin (12 mg/kg body weight, i.p). Rats were sacrificed 48 h after the administration of drugs. 2 mg of protein was used for each assay. Tetramethoxypropane was used as an external standard. Lipid peroxide level is expressed as n moles MDA formed/100 mg protein. Results were expressed relative to control which was taken as 100. The control values are 139+11.7, 149+19 and 76+2.1 for liver homogenate, kidney homogenate and liver mitochondria. Values were Mean±SD for at least 13 animals. *p<0.05, **p<0.01 and ***p<0.001.