Figure 8: Effect of co-administration of mitomycin C and cisplatin with or without the administration of B.aristata on phospholipid composition of liver mitochondria. The animals were divided into four groups of six animals each. Group-1, received saline, group-2, received a single dose of mitomycin C (2 mg/kg body weight, i.p.) and cisplatin (12 mg/kg body weight, i.p). Rats were sacrificed 48 h after the administration of drugs. Group-3, received alcoholic extract of B.aristata (10 mg/100 g body weight, oral) for three days. Group-4 received alcoholic extract of B.aristata (10 mg/100 g body weight, oral) for three days, followed by single dose of mitomycin C (2 mg/kg body weight, i.p) and cisplatin (12 mg/kg body weight, i.p). Rats were sacrificed 48 h after the administration of drugs. All the values are expressed relative to the control, which is taken as 100. The control values of are 24 ± 1.8, 32 ± 2.0, 26 ± 1.2 and 36 ± 1.0 for total phospholipids, phosphatidylcholine, phosphatidylethanolamine and cardiolipin respectively. Values are Mean ± SD for at least 13 animals. *p<0.05, **p<0.01 and ***p<0.001.