Figure 1: Antiproliferative activity of SF1126 and CAL-101 in aggressive B-NHL cell lines. SUDHL-4 and TMD-8 cells were exposed to varying concentrations of SF1126 and CAL-101 for 4 days. Cell viability was assessed by MTS analysis. Points are the means of triplicate determinations SD. Inset: The IC50s of SF1126 and CAL-101 were calculated in these two cell lines. A significant difference of IC50s between SF1126 and CAL-101 was determined by two-tailed t-test (P = 0.0063 in SUDHL-4 and P < 0.0001 in TMD-8).