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Figure 1: (A): SMP30 and TRß expression in human breast cancer cells. SMP30 expression in different breast cancer cell-lines (MCF-7, ZR-75, T47D, MDA MB 231) and immortalized 3T3 fibroblast cell line (non-cancer cell-line) are shown by Western blot analyses and Densitometric histogram for protein band intensity. The histogram of % protein expression was prepared by subtracting the corresponding control. (B): Down regulation of SMP30 in human breast cancer cell line by 17-ß- estradiol. Representative Western blot of total SMP30 protein in response to overnight treatment with 10nM E2 in MCF-7 cells and Densitometric histogram for protein band intensity. The histogram of % protein expression was prepared by subtracting the corresponding control. |