Figure 3: Kaplan-Meier analysis of metastases free survival of all patients (n = 318, UICC stage I-III). The green line denominates the patients receiving simultaneously to the conventional chemo- and/or radiotherapy a supportive Isc-Qu care. The red line denominates the control patients being only treated by conventional chemo- and/or radiotherapy. The median time to the first distant metastasis (i.e. the metastasis-free survival, MFS) was 133+ months in the Isc-Qu group, versus 94 months in the control group (p-Log Rank = 0.002).