| Baseline demographic and prognostic criteria (subgroup analysis with simultaneous ISC-Qu)
initial sample size 318 (106 vs. 212) |
Value (test)
ISC-Qu group
% or mean
(± SD) |
Value
control group
% or mean
(± SD) |
Valid N
test / control
group |
p-values
(Chi-Square, exact Fisher’s, or Mann-Whitney-test) |
| Age at onset of aftercare; mean,(SD) years: |
53.7 (10.9) |
58.3 (9.5) |
106 / 212 |
0.001 |
| Body weight; mean, (SD) kg: |
73.9 (9.9) |
76.8 (13.7) |
101 / 206 |
0.147 |
| Body height; mean, (SD) cm: |
177.4 (7.3) |
171.5 (8.6) |
105 / 208 |
<0.001 |
| Gender males / females % |
76.4 / 23.6 |
56.6 / 43.4 |
106 / 212 |
0.001 |
| Tumor stage “high-risk” (T3 / T4) % |
67.0 |
72.0 |
106 / 211 |
0.364 |
| Tumor stage node positive (N1/2) % |
78.3 |
41.7 |
106 / 211 |
<0.001 |
| Tumor stage grading (G3/G4)
(highly malignant) % |
42.9 |
15.2 |
105 / 211 |
<0.001 |
| Tumor stage UICC III (advanced) % |
78.3 |
41.7 |
106 / 211 |
<0.001 |
| Tumor localization colon or rectal, % |
55.7 / 44.3 |
60.7 / 39.3 |
106 / 211 |
0.400 |
| Tumor postsurgical completely removed (CR, NED) % |
96.2 |
94.0 |
106 / 200 |
0.591 |
| Symptoms present at baseline % |
94.3 |
74.5 |
106 / 212 |
<0.001 |
| Other concurrent diseases
(multi-morbidity) present %: |
43.8 |
64.1 |
105 / 206 |
0.001 |
| 1st surgery to ONC therapy begin time; mean, (SD), months |
1.0 (6.8) |
3.4 (7.8) |
106 / 211 |
<0.001 |
| Aftercare / follow-up duration up to the last information; mean (SD), and median (range), months |
59.1 (25.6)
59 (11-155)) |
49.9 (25.1)
43 (2-144) |
106 / 210 |
<0.001 |
