Variables GG CC GC Chi-square df P–value
Males 28(25.45) 38(34.5) 44(40.0) 2.71 2 0.257
Females 5(19.23) 6(23.07) 15(57.69)      
Age group
<45 4(16.7) 7(29.16) 13(54.17) 1.57 2 0.456
>45 29(25.9) 37(33.0) 46(41.1)      
Stage
Early stage(I & II) 21(41.2) 2(3.9) 25(49.0) 31.12 2 <0.0001
Advanced stage(III & IV) 12(14.1) 42(49.9) 34(40.0)      
Smoking status
Non smoker 11(31.4) 9(25.7) 15(42.8) 1.64 2 0.440
Smoker 22(21.7) 35(34.7) 44(43.6)      
Smoking level(pack year)
Mild(<10) 0(0) 5(55.6) 4(44.4) 5.14 4 0.27
Moderate(<40 13(26.5) 13(26.5) 23(46.9)      
Heavy(>40) 9(21.0) 17(39.5) 17(39.5)      
Smoking type
Cigarette 4(14.2) 13(46.5) 11(39.3) 21.96 8 0.005
Bidi 0(0) 3(27.3) 8(42.3)      
Hookah 10(38.5) 5(19.2) 11(42.3)      
Cigarette + Bidi 1(8.3) 9(75.0) 2(16.6)      
Cigarette + Hookah 8(34.8) 6(26.0) 9(39.2)      
Histological type
SCC 21(26.6) 27(34.2) 31(39.3) 1.36 2 0.506
ADC 12(21.1) 17(29.8) 28(49.1)      
Metastasis
Positive 6(17.1) 22(62.9) 7(20.0) 20.48 2 <0.0001
Negative 27(26.7) 22(21.9) 52(51.5)      
Family history of any cancer
Significant 6(33.3) 5(27.8) 7(38.9) 0.93 2 0.628
Non Significant 27(22.9) 39(33.1) 52(44.0)      
SCC Cytology
Well differentiated 10(23.8) 16(38.1) 16(38.1)     0.75
Moderately differentiated 8(36.4) 7(31.8) 7(31.8)      
Poorly differentiated 4(28.6) 3(21.4) 6(42.8)      
ADC Cytology
Well differentiated 4(36.4) 1(9.0) 6(54.5)     0.37
Moderately differentiated 2(12.5) 5(31.2) 9(56.2)      
Poorly differentiated 5(16.7) 11(36.7) 14(46.7)      
Table 2b: Frequency of survivin(– 31 G/C) polymorphism in cases with respect to different parameters.